Bioinformatics Scientist II

CareDx is a leading precision medicine diagnostics company advancing care in transplant, specialty oncology, and cell therapy. Through our innovative portfolio of molecular diagnostics, digital health solutions, AI-powered data and analytics, and patient support services, we partner with healthcare providers, patients, and biopharma organizations to help inform clinical decision-making and improve patient outcomes. At CareDx, every employee has the opportunity to contribute to innovations that help transform patient care and improve lives. We are seeking a motivated and innovative Bioinformatics Scientist I/Scientist II to join our dynamic R&D team. In this role, you will contribute to the advancement of innovative research, applying your expertise to experiment design, data analysis, algorithm development, and validation studies in support of diagnostic projects. Collaboration is key, as you will interface with cross-functional teams, including bioinformatics, biostatistics, data science, clinical operations, and regulatory affairs. Proficiency in Python scripting, data engineering, and advanced molecular data analysis based on digital PCR and NGS technologies is essential, along with a critical and creative approach to problem-solving. Responsibilities: - Independently initiate, design, and analyze digital PCR and/or NGS experiments to develop and/or improve high-value diagnostic tests. - Develop, optimize, and maintain analysis pipelines to support overall diagnostic product development and commercial launch. - Perform basic analysis of high-dimensional data and collaborate with wet lab scientists, the clinical operations team, and other cross-functional teams for comprehensive data interpretation and troubleshooting and make scientifically supported recommendations. - Provide expert support and guidance regarding experiment design and data analysis for assay development, publication, and decision-making to the broader scientific team. - Collaborate across multiple departments to ensure seamless integration of scientific insights into broader research goals. - Participate in software code review, documentation, testing, and version control. - Work within applicable quality systems such as CLIA/CAP and other regulated software development processes. - Communicate complex computational findings to scientists who may not have a bioinformatics background. - Provide and update commercial-use software tools for LDT diagnostic tests. Minimum Education, Experience, & Specialized Knowledge (Required):  - MS in bioinformatics, molecular biology, chemistry, or a related field with 1-2 years of relevant experience (Scientist I) or 3+ years (Scientist II). Candidates with a BS and significant experience (5+ years) may also be considered. Industry experience developing diagnostic assays is preferred. - Solid foundation in bioinformatics analysis and Python scripting. - Strong interdisciplinary communication skills to foster collaboration and effective knowledge exchange. - Excellent organizational skills with acute attention to detail, ensuring high-quality outputs in a fast-paced environment. - Previous experience in liquid biopsy, working with clinical samples, clinical operations, algorithm and QC development and validation is strongly preferred. Additional Details: Every individual at CareDx has a direct impact on our collective mission to improve the lives of organ transplant patients worldwide. We believe in taking great care of our people, so they take even greater care of our patients. Our competitive Total Rewards package for US Employees includes: - Competitive base salary and incentive compensation - Health and welfare benefits, including a gym reimbursement program - 401(k) savings plan match - Employee Stock Purchase Plan - Pre-tax commuter benefits - And more! - Please refer to our page to view detailed benefits at https://caredx.com/company/careers In addition, we have a Living Donor Employee Recovery Policy that allows up to 30 days of paid leave annually to a full-time employee who makes the selfless act of donating an organ or bone marrow. With products that are making a difference in the lives of transplant patients today and a promising pipeline for the future, it’s an exciting time to be part of the CareDx team. Join us in partnering with transplant patients to transform our future together. CareDx, Inc. is an Equal Opportunity Employer-vets/disabled, and participates in the E-Verify program. By proceeding with our application and submitting your information, you acknowledge that you have read our U.S. Personnel Privacy Notice and consent to receive email communication from CareDx. Certain jurisdictions require notice of how we use and protect your personal information. For more information, please read our Privacy Policy The U.S. EEO posters are available here. Note: We do not accept resumes from headhunters, placement agencies, or other suppliers that have not signed a formal agreement with us. This is the anticipated base salary range for candidates who will work in Waltham, MA. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and length of experience within the job, the type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states. United States $128,000—$160,000 USD