Senior Research Associate, Genome Sciences & Engineering

About Stylus Medicine: Stylus Medicine is developing transformative in vivo genetic medicines to unlock cures. Stylus combines engineered recombinases with non-viral delivery to specifically encode therapeutics. The company’s approach is versatile and modular, with potential therapeutic application across oncology, autoimmune, genetic diseases, and beyond. About the Role: Stylus Medicine is seeking a Senior Research Associate to join our Genome Sciences & Engineering team. In this role, the Senior Research Associate will drive the execution of cell-based assays and high-throughput screening workflows to advance the company’s LSR-based genome editing platforms. This role is ideal for a collaborative, organized, and creative scientist who thrives in a fast-paced environment and enjoys tackling complex problems to expand the frontiers of genome editing. Key Responsibilities & Accountabilities: - Execute cell-based assays and high-throughput (HT) screening workflows that advance platform and program objectives, working both independently and as part of a cross-functional team - Develop and execute arrayed and pooled HT screening campaigns with rigor and reproducibility - Troubleshoot experiments, analyze data, and translate results into actionable scientific insights - Maintain detailed laboratory notebooks and clearly communicate data and findings to the broader scientific team - Partner cross-functionally to advance optimized candidates into translational and preclinical development Qualifications & Skills: - BS with 3+ years or MS with 1+ years relevant experience in cell biology, molecular biology, or a related field - Experience conducting high-throughput cell-based screens; proficiency with primary T cells, hepatocytes, and/or cancer cell lines, working with LNPs preferred - Hands-on experience with gene editing technologies (e.g. CRISPR nucleases, recombinases, base editors, or transcriptional effectors) - Familiarity with laboratory automation platforms for cell-based screening workflows, flow cytometry - Experience with nucleic acid QC methods, including TapeStation, Qubit, NanoDrop, and qPCR - Track record of independently generating precise, reproducible data and performing rigorous quantitative analysis - Clear and approachable communication skills, with the ability to present technical information clearly and concisely to diverse audiences - Exceptional organizational skills and comfort managing complex datasets and overlapping projects - Strategic thinker who effectively plans and prioritizes to maximize scientific impact - Collaborative mindset with a team-first attitude - Creative problem-solver who thrives amid scientific uncertainty Pay Range: $100,000 - $110,000