Principal Associate Scientist

(Boston, MA) Principal Associate Scientist sought by Ascidian Therapeutics, Inc. to design, validate, execute, and interpret experiments to improve therapeutic performance of designer RNA editing molecules & contribute to characterization of drug candidates to support Ascidian’s Roche Collaboration. Req.’s Master’s Deg. in Molecular/Cellular Bio., Bio. Chem. or rel. field & 3 yrs rel. exp. or Bach’s Deg. & 5 yrs rel. exp. Must have experience in RNA therapeutics with a focus on pre-mRNA splicing and protein translation; designing and cloning RNA exon-editing molecules and designing assays to measure RNA editing; optimization and preparation of custom Illumina libraries; bioinformatic analysis of the libraries; cell culture, ddPCR, qPCR and protein extraction and characterization by JESS and western blot, Sanger sequence analysis; use of sequence design and analysis software. No calls. Salary: $ 112,017 to $118,400 per year. The final salary offer will be determined based on several factors, including the candidate’s relevant experience, specific skills, and internal equity.