Sr. Principal Software and AI Engineer

This position is listed on behalf of a partner company, which manages all applications and next steps. Our partner is looking for a Sr. Principal Software and AI Engineer based in the United States. Join a forward-thinking team developing advanced AI-powered applications that transform drug development and clinical trial execution. In this senior technical leadership role, you will shape AI engineering strategy while remaining hands-on in designing, building, and deploying production-grade software. You will lead the development of intelligent, multi-agent systems that streamline clinical protocol generation and improve research workflows. Working closely with clinical experts, medical writers, statisticians, and data scientists, you will translate complex scientific challenges into scalable AI solutions. You will establish engineering standards for reliability, evaluation, security, and regulatory compliance within a validated software development lifecycle. This is an opportunity to influence enterprise AI architecture, mentor engineering talent, and accelerate innovation in a highly regulated, mission-driven environment.